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Microscopic polyangiitis (MPA) is a systemic vasculitis that targets venules, capillaries, arterioles, and small arteries. In view of the caliber of affected vessels, MPA was separated from polyarteritis nodosa at the Chapel Hill Consensus Conference. The condition is primarily associated with necrotizing and crescentic glomerulonephritis and pulmonary capillaritis, but cutaneous and musculoskeletal features are common as well. To analyze the histopathologic and clinical features of MPA, the authors retrospectively reviewed the cases of eight patients (4 men and 4 women; mean age, 64) who presented with cutaneous lesions.
Time from onset to diagnosis was 2 weeks to 3 months in most patients, but it was more than 10 years in two. The most com…