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Crohn and colleagues first described the inflammatory disease of the gastrointestinal tract that bears his name 76 years ago. An estimated 20% to 40% of affected patients have cutaneous involvement. Most often, this appears as fistulas, ulcers, sinus tracts, and vegetant plaques continuous with intra-abdominal disease (e.g., of the abdominal wall and ostomy sites). Metastatic Crohn disease (MCD) refers to cutaneous granulomatous lesions at sites well removed from the gastrointestinal tract (e.g., on the legs, vulva, penis, and face). The typical lesions of MCD are solitary or multiple nodules, plaques, ulcers, lichenoid lesions, and violaceous, perifollicular papules.
The authors of this study of histologic patterns in MCD retrospectively ex…