Primary Cutaneous B-Cell Lymphomas: Radiotherapy or Chemotherapy?

Analysis by WHO-EORTC type identified which lymphomas can be effectively treated by radiotherapy alone and which need more-aggressive treatment.

Primary cutaneous B-cell lymphomas (PCBCLs) are a heterogeneous group of B-cell non-Hodgkin lymphomas that appear in skin without evidence of systemic disease at the time of diagnosis. Investigators in the Netherlands explored the effectiveness of radiotherapy for PCBCL types as classified by the WHO-EORTC system.

This retrospective study of 153 B-cell lymphomas treated over a period of 20 years included 25 primary cutaneous marginal zone B-cell lymphomas (PCMZLs); 101 primary cutaneous follicle center lymphomas (PCFCLs); and 27 primary cutaneous large B-cell lymphomas, leg type (PCLBCL-LTs). All lesions had been treated by local radiotherapy (median dose, 40 Gy). Outcome measures were rates of complete remission, relapse, 5-year relapse-fre…

Reviewing Author

Angelica Selim, MD

Disclosures

Grant / Research support NIH/NCI, The Plastic Surgery Foundation

Angelica Selim, MD

Disclosures

Grant / Research support NIH/NCI, The Plastic Surgery Foundation

Primary Cutaneous B-Cell Lymphomas: Radiotherapy or Chemotherapy?

Topics

Reviewing Author