Vitamin D and Death

Low levels of vitamin D spell higher risk for Death.

Vitamin D protects bone, preserves muscle strength, and regulates cell growth and energy metabolism. It also offers some protection against cancer and other disease, but are these effects really important for health and life expectancy? The answer seems to be a resounding yes.

In a prospective cohort study, researchers measured blood levels of 25-hydroxyvitamin D (25VD) and 1,25 dihydroxyvitamin D (1,25VD) in 3258 consecutive patients undergoing coronary angiography. During a mean follow-up interval of 7.7 years, 737 patients (22.6%) died, 463 from cardiovascular disease (CVD). Low serum 25VD and 1,25VD levels were independently associated with all-cause mortality and with CVD. Patients with 25VD levels in the lowest two quartiles (medians, …

Reviewing Author

Mark V. Dahl, MD

Disclosures

Consultant / Advisory board Ulthera, Inc.; AuBio LifeSciences, LLC; Paris Therapeutics

Equity Elorac, Inc.; Makucell, Inc.; Paris Therapeutics

Editorial boards UpToDate

Leadership positions in professional societiesNational Rosacea Society (Chairman, Medical Board)