Statins’ effect on nonmelanoma skin cancer, minocycline-induced drug hypersensitivity, anti-TNF-α–induced lupus, distinguishing dermatomyositis from lupus erythematosus, incidence of psoriatic arthritis
Statins Not Associated with a Chemopreventive Effect Against Nonmelanoma Skin Cancer
Statins reduce cardiovascular morbidity and mortality but have also been demonstrated to have other protective benefits, including against dementia, fractures, and multiple sclerosis. In addition, pharmacologic effects associated with the prevention of cancer have been ascribed to statin use. Using data gathered during a trial of topical tretinoin as chemoprevention of nonmelanoma skin cancer, researchers analyzed the protective effects of statins.1 They found no effect of statins in the prevention of nonmelanoma skin cancer.
Bottom line: There is no compelling reason, based upon these data, to pursue additional trials of statins.
Sequelae of Minocycline-Induc…
Author
DisclosuresConsultant / Advisory board XOMA; Eli Lilly; Celgene
Equity Various trust accounts
Editorial boards JAMA Dermatology; UpToDate
Leadership positions in professional societies Association of Professors of Dermatology (President-Elect)
DisclosuresConsultant / Advisory board XOMA; Eli Lilly; Celgene
Equity Various trust accounts
Editorial boards JAMA Dermatology; UpToDate
Leadership positions in professional societies Association of Professors of Dermatology (President-Elect)