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Myopathy-related risk for arterial disease, low ambient UV and prevalence of immune disease, questioning the link between isotretinoin and IBD, and a severe combined immunodeficiency variant

Patients with Inflammatory Myopathy, Including Dermatomyositis, at Risk for Arterial Events

Psoriasis is associated with increased prevalence of myocardial infarction, cerebrovascular disease, and peripheral atherosclerotic disease. Now, investigators performed a nested case-control study1 to examine the incidence of arterial events, including acute myocardial infarction (AMI) and cerebrovascular accident (CVA), in patients with dermatomyositis (DM) and polymyositis. They found higher rates of AMI and CVA in these patients than in the general population; the increased rates were linked to comorbidities, including hypertension and hyperlipidemia. Use of steroid-sparing agents, including methotrexate, azathioprine, antimalarial agents, and cyc…

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Patients with Inflammatory Myopathy, Including Dermatomyositis, at Risk for Arterial Events