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A previous epidemiologic study suggested that patients taking calcium-channel blockers (CCBs) were more likely to have chronic eczematous eruptions of the aged (CEEA) than were nonaffected patients (JW Dermatol Dec 14 2007).
To study the association between certain drug classes and CEEA in the U.S., investigators examined data from the University of Utah recorded between 2005 and 2011. Ninety-four patients older than 50 who had at least a 2-month history of a symmetric eruption, were taking at least one medication, and whose biopsy specimens demonstrated spongiotic dermatitis were included and matched for age and sex with 132 controls. Exclusion criteria were history of atopic dermatitis or alternate diagnoses (e.g., bullous pemphigoid, phot…