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Genetics may contribute to male (androgenic) alopecia (AA), but even within families, the expression and penetrance is variable. To address more directly the influence of other factors on AA, investigators studied 92 identical male twins (mean age, 51; range, 23–84), comparing completed questionnaires, four-view standardized photographs, and sputum samples analyzed for testosterone levels. Degree of hair thinning was assessed from photographs by two independent, blinded observers using the Likert scale. Linear regression modeling identified independent predicators of hair loss measures.
Independent factors that contributed to hair loss included genetics, older age, smoking, dandruff, having more children, higher caffeine ingestion, lower BMI…