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Previous reports suggest that the incidence of gastric cancer is declining in the U.S., perhaps because of a decrease in the prevalence of Helicobacter pylori infection. However, the incidence of noncardia gastric adenocarcinoma has not been well described.
In this study, investigators searched the Surveillance, Epidemiology, and End Results (SEER) registries to identify all new cases of noncardia gastric adenocarcinoma in the U.S. from 1973 through 2002. During that time, the overall age-adjusted annual incidence rate declined 23%, from 4.3 to 3.3 cases per 100,000 people. The incidence of cancer confined to the stomach, however, remained stable at about 1 case per 100,000 and actually increased among older groups. Men were twice as likely …