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Oral sodium phosphate solutions (OSPSs) have been associated with renal failure and with deposition of calcium phosphate crystals in renal tubules. This condition has been termed acute phosphate nephropathy; its incidence is assumed to be quite rare, but underreporting is possible.
In the current study, investigators performed a retrospective analysis of renal function changes in 286 patients who had received OSPSs. Participants had undergone colonoscopy or flexible sigmoidoscopy at a single clinic in Texas between 1998 and 2005 and had baseline creatinine levels ≤1.5 mg/dL. All patients had their creatinine levels measured within 6 months of OSPS exposure (to establish a baseline) and then at 6 months and 1 year after the procedure. A cohor…