Associations Between Eosinophilic Esophagitis and Atopic Diathesis

All patients with EoE diagnoses should receive comprehensive allergy testing.

Patients with eosinophilic esophagitis (EoE) frequently report a history of atopic diathesis (asthma, dermatitis, or allergic rhinitis). Although this association has been documented in the literature, the atopy was typically self-reported by patients and not determined by objective testing (Gastrointest Endosc 2004; 59:355).

To determine the extent of allergic sensitization in adults with EoE, investigators completed formal allergy testing in 23 patients with biopsy-proven EoE (median age, 34; 16 men). They determined allergic sensitization to both food-associated and environmental allergens and measured serum IgE levels.

Atopic diathesis was evident in 18 patients; all had allergic rhinitis, 6 had asthma, and 1 had atopic dermatitis. Of the…

Reviewing Author

David A. Johnson, MD

Disclosures

Consultant/Advisory boardMedscape/WebMD; Pfizer; CRH Medical Corporation; Aries

EquityCRH Medical Corporation

Editorial boardsMedscape Gastroenterology

Leadership positions in professional societiesAmerican College of Gastroenterology Research Institute Board of Directors