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A variety of algorithms exist for predicting clinical outcomes in patients with nonvariceal upper gastrointestinal bleeding (UGIB), but none are definitive, and few are applicable to real-life settings. In the present study, investigators evaluated predictors of 30-day mortality among 1020 patients who underwent endoscopic evaluation for nonvariceal UGIB between March 2003 and March 2004. Data were collected prospectively at each of 23 hospitals (both community and tertiary care) in Italy and were entered into a centralized endoscopy database.
High-risk stigmata were present in 33.1% of cases and adherent clots in another 11.7%. Endoscopic therapy was performed in 37.9% of patients, including all those with high-risk stigmata. Proton-pump in…