Survival After Liver Transplantation for Patients with High-Risk HCC

A new prognostic model might help to determine which patients with high-risk HCC are likely to benefit from liver transplantation.

Liver transplantation is the treatment of choice for hepatocellular carcinoma (HCC) in patients whose disease meets the Milan criteria (a single tumor ≤5 cm — or 2 to 3 tumors, each ≤3 cm — with no vascular invasion). Although survival is uncertain for patients whose HCC exceeds these criteria (high-risk HCC), small retrospective studies have suggested that certain disease characteristics are associated with improved survival after transplantation. Now, investigators have developed a prognostic model that might help to determine which patients with high-risk HCC are likely to benefit from liver transplantation.

Physicians from 36 international transplantation centers used an Internet-based survey to supply data on 1556 HCC patients. Of these…

Reviewing Author

Atif Zaman, MD, MPH

Disclosures

Nothing to disclose

Atif Zaman, MD, MPH

Disclosures

Nothing to disclose