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Capsule endoscopy (CE) is a less invasive method of detecting colorectal cancer (CRC) than colonoscopy. Now, a CE system that incorporates a battery-conserving “sleep mode” has been developed specifically to visualize the colon. Using colonoscopy as the standard of comparison, researchers evaluated the PillCam COLON capsule's sensitivity and specificity for identifying polyps, advanced adenomas, and cancer.
The prospective, international, industry-sponsored study involved 328 patients (mean age, 59) with known or suspected colorectal neoplasia. Patients underwent extensive bowel preparation before ingestion of capsules. The capsule had cameras on both ends; each camera acquired images at two frames per second. Colonoscopy was performed after…