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Previous studies have suggested that greater coffee intake is associated with lower risk for hepatocellular carcinoma (JW Gastroenterol Aug 3 2007) as well as with lower alanine aminotransferase (ALT) levels and lower risks for cirrhosis and chronic liver disease. To examine a potential association between coffee consumption and liver disease progression, investigators assessed 766 patients enrolled in the Hepatitis C Antiviral Long-term Treatment against Cirrhosis (HALT-C) trial, which evaluated the use of long-term peginterferon in hepatitis C virus (HCV)-infected patients with advanced fibrosis who failed to achieve sustained virologic response to previous peginterferon and ribavirin therapy.
Participants reported coffee and tea consumpti…