Predictors of Unfavorable Outcomes After Endoscopic Removal of Submucosal Invasive Colorectal Tumors

Numerous studies involving patients who have undergone surgical resection after endoscopic removal of colorectal tumors have suggested that poor tumor differentiation, venous or lymphatic invasion, involvement of the resection margin with cancer, and incomplete endoscopic resection are predictors of unfavorable outcomes. However, little is known about risk factors in patients who have been treated only endoscopically.

Now, researchers have retrospectively examined outcomes of patients who underwent endoscopic resection for submucosally invasive (T1) colorectal cancers between 1974 and 2002 at a hospital in Germany. Among 390 patients with follow-up data for ≥24 months, 141 underwent surgery after the endoscopic resection and 249 did not. Ove…