Loading...
Patients with chronic ulcerative colitis (UC) are at excess risk for both colorectal cancer and dysplasia — both of which occur most frequently in the left colon. Therefore, experts suggest that endoscopists conduct extensive biopsies in the left colon during surveillance colonoscopy. Now, researchers have retrospectively studied progression of low-grade dysplasia (LGD) to advanced neoplasia according to location in the colon among 121 patients with UC.
LGD was distal to the splenic flexure in 68 patients and proximal in 53. Eight patients progressed to high-grade dysplasia and seven to colorectal cancer during a median follow-up of 37.5 months. In 14 of these 15 patients, the more advanced lesion was found on the same side of the colon as t…