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Colorectal cancer screening tests are only effective if invited patients actually undergo the tests (i.e., adherence). In previous trials comparing the acceptance of computed tomographic colonography (CTC) versus conventional colonoscopy, only one study examined adherence, finding similar rates of about 18% (Am J Gastroenterol 2004; 99:1145). Now, results of the largest trial to date show better adherence rates for CTC than colonoscopy.
In this study, investigators randomized 8844 people aged 50 to 75 in the Netherlands to be offered colonoscopy or CTC in a 2:1 ratio. CTC was performed with a noncathartic preparation in which patients received only three 50-mL doses of iodinated contrast before the procedure.
The adherence rate was higher for…