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Studies estimating the risk for colorectal cancer in patients who have undergone adenoma removal versus the general population have yielded widely discordant results. These discrepancies can sometimes be explained by variability in patient eligibility requirements, types of follow-up, and source populations.
Now, investigators have conducted a retrospective cohort study to compare the risk for colorectal cancer after adenoma removal with that in the general population. Using population-based data registries, they identified 5779 residents of Burgundy, France, who had undergone a first-time adenoma removal and recorded subsequent cancer diagnoses. Median follow-up time from the date of adenoma diagnosis was 7.7 years.
Results were as follows:
E…