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Recent studies have described the benefits of fecal transplantation in patients with recurrent Clostridium difficile infections (JW Gastroenterol Mar 30 2012 and JW Gastroenterol Jun 4 2010).
To study the long-term effects of fecal transplantation, investigators conducted a multicenter follow-up study of 77 adults (mean age, 65; 73% women) who underwent the procedure for refractory C. difficile colitis. On average, patients had experienced diarrhea symptoms for 11 months and had failed to respond to five antimicrobial regimens prior to fecal transplantation.
Results were as follows:
Diarrhea symptoms resolved in 74% of patients in ≤3 days.
Diarrhea symptoms resolved in 82% of patients and improved in 17% within an average of 5 days (range, 1–60…