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After reperfusion therapy for ischemic stroke, the ischemic tissue can (1) be salvaged (totally or partially), (2) not be salvaged, or (3) undergo secondary (delayed) injury after initial apparent salvage. These authors aimed to characterize tissue outcome in patients with ischemic stroke who had successful recanalization after intra-arterial thrombolysis that was started within 6 hours of stroke onset. Eighteen patients underwent MRI, which included diffusion-weighted imaging (DWI), T2-weighted imaging (T2-WI), and perfusion imaging, before, immediately after, and 7 days after treatment.
Of the 18 patients, 10 had no tissue salvage, and 8 showed partial or total reversal of the ischemic lesion (identified on pretreatment DWI) immediately af…