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To identify the clinical characteristics and outcomes of myasthenia gravis (MG) in children, researchers in India studied the case records of 77 pediatric and 250 “adult” patients with presumably autoimmune (rather than congenital or transient) MG. The pediatric group had MG onset from age 1 through 15 years; older patients had onset after age 15.
The findings focused on the pediatric group. Median age of onset was 8 years; 30% had ocular MG, and the rest had generalized MG. In 27% of cases, the disease was restricted to ocular muscles throughout its course. Family history of MG was positive in 10%. Three also had epilepsy and one had migraines; none had associated autoimmune diseases. Repetitive motor-nerve stimulation showed a decrement in…