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Deep brain stimulation of the internal segment of the globus pallidus (GPi-DBS) has been reported effective in reducing motor disability and improving quality of life for medication-refractory primary generalized dystonia. In patients with medication-refractory cervical dystonia (CD), the experience with GPi-DBS is limited.
Researchers now report a single-site, open-label study in which 10 consecutive patients with CD underwent bilateral GPi-DBS. Patients had insufficient benefit or intolerable side effects from medical intervention, marked disability, and no major cognitive or neuropsychiatric conditions. They were assessed at 6- to 12-month intervals with the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) and were divided into…