Prompt TIA and Minor Stroke Management

An unacceptably high proportion of patients with transient ischemic attack (TIA) or minor stroke are underinvestigated and undertreated, especially during the period of highest risk for recurrent stroke (the 7 days after the event). Investigators for the Early use of eXisting PREventive Strategies for Stroke (EXPRESS) study previously reported that relatively rapid management of TIA and minor stroke was effective in reducing 90-day recurrent-stroke risk among patients referred to a specialized clinic (JW Neurol Jan 15 2008). The authors now report further analysis of the study data for the effects of prompt management on 90-day hospital admissions, hospital bed-days, and costs, and new disability at 6 months.

For phase one of EXPRESS, patients with TIA or minor stroke received assessment in an appointment-based clinic and then were sent back to their primary care physicians to implement treatment recommendations. For phase two, primary care physicians sent patients to the clinic immediately after presentation (without an appointment), and treatment was initiated promptly in the clinic after the diagnosis was confirmed. As previously reported, the 90-day recurrent-stroke risk dropped significantly (by 80%) from phase one to phase two.

The new analysis shows that, compared with phase one, phase two patients had significantly fewer hospital admissions for recurrent stroke within 90 days (2% vs. 8%), hospital bed-days (672 vs. 1957), and instances of new disability at 6 months (6% vs. 11%). Average hospital costs attributed to vascular causes were also significantly lower in phase two (£432 vs. £1056 per patient).