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Mortality in patients with gliomas is influenced by factors including age, performance status, tumor size and location, histopathologic type, and WHO grade. In previous studies, WHO grade I and II gliomas (a.k.a., low-grade gliomas [LGGs]) occurred significantly more frequently in younger adults (age <60), so less is known about LGGs in older adults (age ≥60). To identify prognostic factors, these researchers retrospectively examined data on presentation, treatment course, and outcome of supratentorial LGGs occurring in 62 older adults and 704 younger adults seen at one institution.
Older patients were significantly more likely than younger patients to present with a clinical deficit (with cognitive deficits more frequent than seizures), a l…