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To revise and update the 2005 American Academy of Neurology practice parameters for treating essential tremor (ET), the Quality Standards Subcommittee examined the ET literature from 2004 to April 2010. A computer-based search identified 589 articles, of which 252 were scrutinized fully by two or more committee members.
The committee concluded that the following recommendations from 2005 should remain unchanged:
Propranolol and primidone should be offered for limb tremor (Level A).
Drugs that are probably effective and should be considered (Level B) are alprazolam, atenolol, gabapentin, sotalol, and topiramate for limb tremor and propranolol for head tremor.
Treatments that remain categorized as possibly effective for limb tremor (Level C) are …