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To investigate the pathophysiology of sports-related concussion (SRC) in children, researchers evaluated 12 children aged 11 to 15 years who had experienced an SRC. Neurocognitive testing and advanced magnetic resonance imaging (MRI) investigations were conducted at three time points after injury — within 72 hours, at 14 days, and at 30 days or later — to look for evidence of structural injury, metabolic alterations, and changes in cerebral blood flow (CBF). CBF was measured with phase-contrast angiography.
Neurocognitive testing confirmed that, compared with age- and gender-matched controls, concussed patients had significantly worse total symptom scores and prolonged reaction times, which resolved by 14 days and by final testing, respectiv…