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The goal of this study was to identify clinical characteristics and response to treatment of autoimmune epilepsy. The authors retrospectively reviewed data from 32 patients followed in a specialty autoimmune neurology clinic. The authors define autoimmune epilepsy as (1) epilepsy as the exclusive or predominant symptom, and (2) a suspected autoimmune pathogenesis based on detection of neural autoantibodies, inflammatory cerebrospinal fluid (CSF) findings (leukocytosis or CSF-exclusive oligoclonal immunoglobulin bands), or magnetic resonance imaging (MRI) features of inflammation (T2 hyperintensity, contrast enhancement, or restricted diffusion).
Clinical features were heterogeneous but most commonly included the following:
High seizure freque…