The findings of a Japanese study highlight the importance of multidisciplinary evaluation to determine subarachnoid hemorrhage risk and to formulate individualized management plans.
Widespread use of brain imaging has led to frequent identification of unruptured intracranial aneurysms. The patients and clinicians face a difficult choice, because no randomized trial has addressed whether and when to treat unruptured aneurysms. Thus, the management of these aneurysms rests on balancing their natural history with the risks of treatment. Much of our knowledge about this natural history comes from the International Study of Unruptured Intracranial Aneurysms (ISUIA; Lancet 2003; 362:103). Now, a prospective, observational study provides additional data.
Between 2001 and 2004, 5720 patients with 6697 unruptured saccular aneurysms ≥3 mm in diameter were enrolled at 283 centers across Japan. Follow-up was censored at the time of…
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DisclosuresSpeaker’s bureauGenentech
Grant / Research supportNational Institutes of Health/National Institute of Neurological Disorders and Stroke; Michael Goldberg Stroke Research Fund
Editorial boardsPLOS One; Scientific Reports
Leadership positions in professional societiesNeurocritical Care Society (Research Committee Member)
DisclosuresSpeaker’s bureauGenentech
Grant / Research supportNational Institutes of Health/National Institute of Neurological Disorders and Stroke; Michael Goldberg Stroke Research Fund
Editorial boardsPLOS One; Scientific Reports
Leadership positions in professional societiesNeurocritical Care Society (Research Committee Member)