Loading...
Withdrawal symptoms from selective serotonin reuptake inhibitors (SSRIs) are well known. Withdrawal symptoms in newborns -- notably, convulsions, irritability, abnormal crying, and tremor -- have been described in a few reports. Investigators searched a database containing over 3 million reports made to the WHO Collaborating Centre for International Drug Monitoring and identified 93 infants who had neonatal seizures or other withdrawal symptoms associated with maternal use of SSRIs. Only 2 of the 93 cases involved premature births.
Neurologic symptoms were the most common manifestations of neonatal withdrawal. Thirteen babies had convulsions; other neurologic symptoms included nervousness, hypertonia, abnormal crying, tremor, and involuntary…