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In this occasional column, Journal Watch Psychiatry editors provide brief comments about review articles as another way to assist readers who wish to keep abreast of developments in the field of psychiatry. The annotations in this column were written by Barbara Geller and Jonathan Silver.
How strong is the evidence for interactions between environmental stressors and the serotonin transporter gene? These editorialists review studies on interactions between polymorphisms in the serotonin transporter gene and childhood adversity.1 Some studies support the initial association by Caspi et al. between the short allele and depression vulnerability after stress (see Journal Watch Psychiatry Oct 8 2003); others report a result in the opposite direct…