Caffeine, one of the world’s most used substances, improves wakefulness, mood, and attention and may increase apoptosis (which might protect against carcinogenesis). A population-based study and an animal study have recently examined several possible benefits of caffeine.
In the “Three City Study” in France, 4197 women and 2820 men without dementia diagnoses (mean age, 74) underwent several cognitive tests three times over 4 years. Caffeine consumption and multiple other demographic, medical, and lifestyle variables were analyzed. There was no relation between cognitive decline and caffeine consumption for men. Among women, however, a dose-response relation was found: After other variables were controlled for, drinking at least three cups of…
Reviewing Author
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)