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Yet another study adds considerations for managing depression during pregnancy. These researchers prospectively observed 238 pregnant women; 131 had neither depression nor SSRI treatment, 14 had continuous major depression but no SSRI treatment, 48 had continuous SSRI treatment, 22 had “partial depression” (i.e., ≥1 depression-free trimesters) and no SSRIs, and 23 had partial SSRI treatment (≥1 SSRI-free trimesters).
Smoking rates were similar across groups. Exclusion criteria included substance use disorder or exposure to class D or X agents. Prenatal assessments occurred at weeks 20, 30, and 36. Untreated depressed women sustained markedly significantly worse depressive symptoms than other women. Rates of preterm birth (i.e., birth <37 wee…