Specific tests appear to predict time to mild cognitive impairment, but they might be difficult to implement routinely in a clinical setting.
Patients complaining of memory problems are generally most concerned about whether these are signs of early dementia. In fact, many individuals with amnestic mild cognitive impairment (aMCI), which is characterized by impairments in episodic memory, go on to develop Alzheimer disease (AD). These researchers attempted to predict the time to conversion to aMCI in 241 cognitively healthy elders who were enrolled as controls in a longitudinal memory disorder study and who had at least two study visits (baseline mean age, 72).
The researchers performed both subjective and objective cognitive assessments, including examinations of orientation, comprehension, expression, recent memory, remote memory, learning, abstract thinking, perception, praxis,…
Reviewing Author
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)