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The association between discord in intimate relationships (dyadic discord) and depression is well established. In this manufacturer-supported study, researchers examined how baseline dyadic discord affects chronic depression after acute treatment (nefazodone, cognitive behavioral analysis system of psychotherapy, or combination treatment); the data came from a 12-week, randomized study involving 681 outpatients with chronic, nonpsychotic depression (JW Psychiatry Jul 1 2000). Of 316 participants living with an intimate partner, 171 completed assessments of relationship issues.
At baseline, 53% of this subgroup reported dyadic discord. Depression remission rates were significantly lower in the presence of baseline dyadic discord than in its a…