Complaints of problems with sleep and fatigue are common after traumatic brain injury (TBI). In two publications, a research group confirms the frequency of this problem and explores the efficacy of modafinil.
Investigators performed a 3-year follow-up of 51 patients who had previously been assessed 6 months after TBI (Brain 2007; 130:1873). Patients completed a structured telephone interview and a written questionnaire, including standardized scales for sleepiness, fatigue, anxiety, and depression. Sleep-wake disturbances were found in 67% of respondents, but only 10% had insomnia. Hypersomnia was present in 27% (6-month rate, 22%). Although 51% reported fatigue-associated symptoms, only 35% met standardized criteria for fatigue (6-month ra…
Reviewing Author
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)
DisclosuresRoyaltiesTextbook of Traumatic Brain Injury, 2nd and 3rd editions
Editorial BoardsUpToDate; Journal of Neuropsychiatry and Clinical Neuroscience
Leadership Positions in Professional SocietiesNorth American Brain Injury Association (Board Member); National Institute on Disability, Independent Living, and Rehabilitation Research (Chair of Data Monitoring Safety Board for study of donepezil on cognition after traumatic brain injury)