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Depression is known to be a risk factor for bad outcomes of ischemic heart disease (IHD) in older people, but less is known about its impact on cardiac disease in younger people. In this study, researchers used a national mortality database to determine survival of 7641 people who had undergone structured diagnostic interviews a median of 15 years earlier (at a mean age of 28) as part of a national survey of health and nutrition.
At baseline, 5.4% of the group had a lifetime history of unipolar depression, and 1.6% had a lifetime history of bipolar depression; 5.5% reported a previous suicide attempt. At follow-up, 51 participants had died from cardiovascular disease (IHD, 28). After adjustment for age, sex, and traditional IHD risk factors,…