Loading...
In the 1930s, the original rationale for convulsive therapy as a treatment for schizophrenia was that schizophrenia and epilepsy never occurred in the same person, but several studies since that time have noted the association of epilepsy with “schizophrenia-like psychoses.” Now, researchers have used Finnish national registry data on 9653 families and 23,404 of their offspring born in Helsinki between 1947 and 1990 to examine the co-occurrence of epilepsy with schizophrenia, unipolar and bipolar affective psychoses, and nonaffective psychoses (e.g., delusional disorder), within individuals and within families.
Compared to subjects without epilepsy, those with epilepsy were significantly more likely to have schizophrenia (hazard ratio, 8.5),…