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Patients and clinicians are understandably concerned about the effects of antenatal depression and medication use on both neonatal health and children's growth and development over longer periods. Using a subsample of subjects with complete longitudinal data from a prospective study (JW Psychiatry Apr 13 2009), investigators examined the development through age 1 year of children whose mothers took selective serotonin reuptake inhibitors (SSRIs) during pregnancy (n=46), whose mothers had major depression but received no antidepressants during pregnancy (n=31), or whose mothers were never depressed and were never treated with SSRIs (n=97; control group).
Women on SSRIs had a modestly higher mean prepregnancy body-mass index than controls. Ana…