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To investigate whether the absorption rate of insulin could be improved and the glycemic response to a meal diminished, a special "sprinkler" needle was tested in two studies of insulin-dependent diabetics. The device is an ordinary 25 mm needle; however, it has 14 small holes in the walls and a sealed tip.
In an absorption study, 10 patients received an injection after breakfast of 8 U of iodine-125-labelled insulin at two separate sites in the abdominal wall. One injection was administered through a conventional needle, the other through the sprinkler. The dose absorbed during the first 30 minutes was significantly greater with the sprinkler needle.
In a meal study, 11 patients were injected with 10 U of short-acting insulin before a standa…