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During 1993, Journal Watch reported many exciting and important advances. As the new year begins, the Editors have chosen what we believe are the developments of greatest interest to our readers -- those that may have the greatest impact on our practices in the years ahead. THE CONQUEST OF INVASIVE HIB DISEASE Not long ago, H. influenzae type b (Hib) was the leading cause of bacterial meningitis and acute epiglottitis in young children. Thanks to new vaccines, the scourge of invasive Hib disease in the U.S. has been dramatically reduced. The original polysaccharide vaccine was replaced by much more immunogenic vaccines that are now given as a series of four injections starting at 2 months of age. Three back-to- back reports this year testif…