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Adenosine is effective for terminating supraventricular tachycardia (SVT), which uses the atrioventricular node as part of its reentrant circuit. However, catecholamines, which are sometimes required to induce SVT, can have antagonistic effects on adenosine action, and whether catecholamine-induced SVT responds to adenosine is not clear.
This study compared the effects of adenosine in two groups: 13 patients with SVT induced by pacing alone, and 8 patients who required isoproterenol to induce SVT. All patients had either AV-node reentrant tachycardia or reciprocating tachycardia.
Adenosine successfully terminated tachycardia in all cases. The average doses needed to terminate SVT did not differ significantly between patients with catecholamin…