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Researchers used data from a large prospective U.S. cohort study of 27,840 healthy women (age ≥45) to clarify the relation between migraine, with or without aura, and cardiovascular and cerebrovascular disease. Of the 3610 women (13%) with active migraine at baseline (i.e., within the previous year), 1434 (40%) reported experiencing migraine with aura.
During a mean follow-up of 10 years, 251 ischemic strokes, 249 myocardial infarctions, 130 deaths from ischemic cardiovascular disease, 514 coronary revascularizations, and 408 cases of new-onset angina were reported. In multivariate analyses adjusted for age and several cardiovascular risk factors, no association was found between any of these outcomes and active migraine without aura, but si…