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Although ovarian cancer is typically diagnosed late because signs and symptoms are often nonspecific, about 25% of affected women will have early-stage disease at diagnosis. Despite worldwide recommendations that standard therapy include a staging procedure with lymphadenectomy, many women with early ovarian cancer are inadequately staged. Using information from the Surveillance, Epidemiology, and End Results (SEER) database, U.S. investigators compared 2862 women with surgically confirmed stage I ovarian cancer (all underwent lymphadenectomy and had negative nodes) to 3824 women with clinical stage I ovarian cancer who did not undergo lymphadenectomy.
The 5-year disease-specific survival rate was 92.6% with lymphadenectomy and 87.0% without…