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Increasingly, researchers are focusing on possible extraskeletal manifestations of vitamin D deficiency (e.g., weakness and falls) in elderly populations. In the latest study, Dutch investigators evaluated the association between serum levels of 25-hydroxyvitamin D [25(OH)D] and physical performance scores (which assessed coordination, proximal muscle strength, and balance) in a population-based cohort of 1234 people aged 65 or older (mean age, 75).
Up to a threshold of 20 ng/mL, higher levels of 25(OH)D correlated with better physical performance scores after adjusting for potentially confounding variables such as age, sex, and number of chronic diseases. Beyond this threshold, physical performance was similar at all levels of 25(OH)D. Phys…