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Eosinophilic esophagitis (EE) is recognized increasingly in both children and adults. Adults present mainly with solid food dysphagia and food impaction; endoscopic findings include multiple rings, furrows, nondistal strictures, and mucosal friability — or sometimes normal mucosa. In this prospective study, Mayo Clinic researchers sought to determine the prevalence and predictors of EE among 376 consecutive adults (age range, 18–60) referred for endoscopy to evaluate dysphagia.
Of 222 patients who underwent midesophageal biopsies, 33 had histologic evidence of EE. Ten of these 33 patients had endoscopic features suggesting EE, 10 had normal mucosa at endoscopy, and the remainder had various endoscopic findings such as reflux esophagitis and …