Loading...
Bone-mineral density (BMD), expressed statistically as standard deviations above or below the BMD of a healthy young adult (T-scores), is used widely in making osteoporosis treatment decisions. However, it is only one of many factors that determine absolute risk for fracture.
Recognizing the limitations of relying on BMD alone, researchers have developed a new paradigm to address osteoporosis and its treatment. A research team sponsored by the World Health Organization (WHO) has analyzed data from nine population-based studies conducted worldwide and has created a statistical model that predicts 10-year risk for hip and other major fractures. The model, called “FRAX,” incorporates BMD, age, sex, body-mass index, and seven other risk factors;…