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In the randomized SAPPHIRE trial, U.S. investigators compared carotid stenting and carotid endarterectomy (CEA) in 334 patients with symptomatic or asymptomatic carotid stenosis. All patients were considered at high surgical risk by virtue of comorbidities, age, or anatomic considerations. At 1 year, 12% of stented patients versus 20% of CEA patients (P=0.05) had experienced the primary endpoint of death, stroke, or myocardial infarction at 30 days, or ipsilateral stroke or neurologic death after 31 days (Journal Watch Oct 29 2004). Now, the researchers present longer-term outcomes.
At 3 years, the estimated incidence of the above-noted endpoint was 26% in the stent group and 30% in the CEA group, a nonsignificant difference. In addition, no…