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Routine prophylaxis for deep venous thrombosis (DVT) has not been recommended due to insufficient data. Investigators randomized 1761 patients who underwent knee arthroscopy in an Italian clinic to wear full-length graduated compression stockings for 7 days or to receive daily subcutaneous low-molecular-weight heparin (LMWH) for 7 or 14 days.
After 3 months, the incidence of the primary efficacy endpoint — asymptomatic proximal DVT, proximal or distal symptomatic DVT, or death from any cause — was significantly lower in the LMWH groups (0.9% in both the 7-day and 14-day groups) than in the stocking group (3.2%). These primary endpoint events were more common in patients who underwent meniscectomy than in those who underwent diagnostic arthro…