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Greater use of sick leave from work is associated with long-term elevated all-cause mortality. In this prospective cohort study, investigators followed 6478 London-based government office workers (age range, 35–55) for 13 years to determine whether diagnosis-specific sick leave predicted all-cause mortality.
During follow-up, 288 participants died, and 1906 participants (29%) had one or more extended absences (≥7 days) during a 3-year period. After adjustment for age, sex, and employment grade, all-cause mortality among these 1906 participants was significantly higher (1.7 times) than mortality among those without extended absences. Hazard ratios for all-cause mortality were significantly higher for absences caused by circulatory illness (4.…